We provide process chemistry and CMC guidance for development of preclinical and clinical API and their intermediates.

What We Do

JKonsult provides its core expertise in the chemical process and development of small molecules and the synthesis, development and scale-up of fine chemicals, intermediates and active pharmaceutical ingredients.

We are specialists in this field and offer targeted and pragmatic suggestions to direct or help guide your team or contractor to an appropriate solution, in line with the phase of development of your product – whether in research, development or commercial manufacture.

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Meet Our Consultants

Each of our consultants have at least 20 years’ scientific and industrial experience working within the UK and internationally, with pharma/biotech clients and with CRO’s.

Our joint expertise began from lab-based beginnings, through formal qualification, postdoctoral periods abroad and leadership roles within CRO’s. During the last decade, our consultants have additionally been delivering lectures and training sessions.

Dr John Knight

Process Chemistry & CMC Consultant

John Knight

John’s main professional focus is in working with early stage clinical development candidates and transfer to plant, often working with small pharma companies where he helps with CMC issues related to material supplies for toxicological studies, Phase I and II clinical trials.
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Dr John Kremers

Process Chemistry & CMC Consultant

Dr John Kremers

John’s main professional focus is in early-stage chemical development and scale-up projects for GMP and non-GMP products to aid in securing material supplies for toxicological studies and Phase I and II clinical trials. His expertise extends to the scale-up of fluorination chemistry and to the synthesis of polymers and dendrimers.
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JKonsult provides expertise in chemical development of fine chemicals, intermediates and active pharmaceutical ingredients including synthetic route design and evaluation, process development and scale-up…….

Chemical Process Development Of Small Molecules

JKonsult provide pragmatic and phase-appropriate scientific, technical, and strategic advice for the development of new chemical entities that are in the preclinical and early clinical stages of development through……..

Clinical Development Cmc Support

JKonsult provide guidance on the requirements to screen for and select the preferred salt (or co-crystal) version and subsequent studies to evaluate the polymorphic landscape ……

Salt Selection Polymorphism And Crystallisation

JKonsult consultants are highly experienced as teachers and mentors, with an excellent track record in developing and mentoring staff. Our consultants are often engaged to support ……

Staff Development Mentoring Training